Cortical Excitability and Activation of TrkB Signaling During Rebound Slow Oscillations Are Critical for Rapid Antidepressant Responses

Rapid antidepressant effects of ketamine become most evident when its psychotomimetic effects subside, but the neurobiological basis of this “lag” remains unclear. Laughing gas (N(2)O), another NMDA-R (N-methyl-d-aspartate receptor) blocker, has been reported to bring antidepressant effects rapidly...

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Vydáno v:Mol Neurobiol
Hlavní autoři: Kohtala, Samuel, Theilmann, Wiebke, Rosenholm, Marko, Penna, Leena, Karabulut, Gulsum, Uusitalo, Salla, Järventausta, Kaija, Yli-Hankala, Arvi, Yalcin, Ipek, Matsui, Nobuaki, Wigren, Henna-Kaisa, Rantamäki, Tomi
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505519/
https://ncbi.nlm.nih.gov/pubmed/30288695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1364-6
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