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Cortical Excitability and Activation of TrkB Signaling During Rebound Slow Oscillations Are Critical for Rapid Antidepressant Responses

Rapid antidepressant effects of ketamine become most evident when its psychotomimetic effects subside, but the neurobiological basis of this “lag” remains unclear. Laughing gas (N(2)O), another NMDA-R (N-methyl-d-aspartate receptor) blocker, has been reported to bring antidepressant effects rapidly...

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Dades bibliogràfiques
Publicat a:Mol Neurobiol
Autors principals: Kohtala, Samuel, Theilmann, Wiebke, Rosenholm, Marko, Penna, Leena, Karabulut, Gulsum, Uusitalo, Salla, Järventausta, Kaija, Yli-Hankala, Arvi, Yalcin, Ipek, Matsui, Nobuaki, Wigren, Henna-Kaisa, Rantamäki, Tomi
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505519/
https://ncbi.nlm.nih.gov/pubmed/30288695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-018-1364-6
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