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Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure

BACKGROUND: Epidemiological studies have found that prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) is associated with increased risk for neural tube defects (NTDs). Aberrant DNA methylation, excessive apoptosis, and oxidative stress have been implied as the mechanism underlying the ass...

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Pubblicato in:Clin Epigenetics
Autori principali: Huang, Yun, Ren, Aiguo, Wang, Linlin, Jin, Lei, Lin, Shanshan, Li, Zhiwen, McDonald, Jasmine A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505285/
https://ncbi.nlm.nih.gov/pubmed/31064411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0673-6
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