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Casp8 hypomethylation and neural tube defects in association with polycyclic aromatic hydrocarbon exposure

BACKGROUND: Epidemiological studies have found that prenatal exposure to polycyclic aromatic hydrocarbons (PAHs) is associated with increased risk for neural tube defects (NTDs). Aberrant DNA methylation, excessive apoptosis, and oxidative stress have been implied as the mechanism underlying the ass...

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Detalhes bibliográficos
Publicado no:Clin Epigenetics
Main Authors: Huang, Yun, Ren, Aiguo, Wang, Linlin, Jin, Lei, Lin, Shanshan, Li, Zhiwen, McDonald, Jasmine A.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6505285/
https://ncbi.nlm.nih.gov/pubmed/31064411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0673-6
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