Neural Tube Defects and ZIC4 Hypomethylation in Relation to Polycyclic Aromatic Hydrocarbon Exposure

BACKGROUND: Epigenetic dysregulation is one of the postulated underlying mechanisms of neural tube defects (NTDs). Polycyclic aromatic hydrocarbons (PAHs), a group of environmental pollutants that are reported as a risk factor of NTDs, may cause decreased genome-wide DNA methylation. With DNA extrac...

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Pubblicato in:Front Cell Dev Biol
Autori principali: Huang, Yun, Lin, Shanshan, Wang, Chengrong, Pi, Xin, Jin, Lei, Li, Zhiwen, Wang, Linlin, Ren, Aiguo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2020
Soggetti:
Cell and Developmental Biology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7701213/
https://ncbi.nlm.nih.gov/pubmed/33304900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2020.582661
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