Toxoplasma Effector GRA15-Dependent Suppression of IFN-γ-Induced Antiparasitic Response in Human Neurons

Toxoplasma gondii is an important human and animal pathogen that causes life-threatening toxoplasmosis. The host immune system produces interferon-γ (IFN-γ) to inhibit T. gondii proliferation. IFN-γ-inducible indole-2,3-dioxygenase 1 (IDO1), which mediates tryptophan degradation, has a major role in...

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Detalles Bibliográficos
Publicado en:Front Cell Infect Microbiol
Autores principales: Bando, Hironori, Lee, Youngae, Sakaguchi, Naoya, Pradipta, Ariel, Sakamoto, Ryoma, Tanaka, Shun, Ma, Ji Su, Sasai, Miwa, Yamamoto, Masahiro
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2019
Materias:
Cellular and Infection Microbiology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504700/
https://ncbi.nlm.nih.gov/pubmed/31119110
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcimb.2019.00140
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