Toxoplasma Effector TgIST Targets Host IDO1 to Antagonize the IFN-γ-Induced Anti-parasitic Response in Human Cells

Toxoplasma gondii is an important human and animal pathogen that causes life-threatening toxoplasmosis. Interferon-γ (IFN-γ) is critical for anti-T. gondii cell-autonomous immunity in both humans and mice. To proliferate efficiently within the hosts, virulent strains of T. gondii can suppress IFN-γ-...

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Vydáno v:Front Immunol
Hlavní autoři: Bando, Hironori, Sakaguchi, Naoya, Lee, Youngae, Pradipta, Ariel, Ma, Ji Su, Tanaka, Shun, Lai, De-Hua, Liu, Jianfa, Lun, Zhao-Rong, Nishikawa, Yoshifumi, Sasai, Miwa, Yamamoto, Masahiro
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2018
Témata:
Immunology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156249/
https://ncbi.nlm.nih.gov/pubmed/30283439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02073
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