Toxoplasma gondii TgIST co-opts host chromatin repressors dampening STAT1-dependent gene regulation and IFN-γ–mediated host defenses

An early hallmark of Toxoplasma gondii infection is the rapid control of the parasite population by a potent multifaceted innate immune response that engages resident and homing immune cells along with pro- and counter-inflammatory cytokines. In this context, IFN-γ activates a variety of T. gondii–t...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Gay, Gabrielle, Braun, Laurence, Brenier-Pinchart, Marie-Pierre, Vollaire, Julien, Josserand, Véronique, Bertini, Rose-Laurence, Varesano, Aurélie, Touquet, Bastien, De Bock, Pieter-Jan, Coute, Yohann, Tardieux, Isabelle, Bougdour, Alexandre, Hakimi, Mohamed-Ali
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2016
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4995087/
https://ncbi.nlm.nih.gov/pubmed/27503074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160340
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