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Characterization of a Toxoplasma effector uncovers an alternative GSK3/β-catenin-regulatory pathway of inflammation

The intracellular parasite Toxoplasma gondii, hijacks evolutionarily conserved host processes by delivering effector proteins into the host cell that shift gene expression in a timely fashion. We identified a parasite dense granule protein as GRA18 that once released in the host cell cytoplasm forms...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: He, Huan, Brenier-Pinchart, Marie-Pierre, Braun, Laurence, Kraut, Alexandra, Touquet, Bastien, Couté, Yohann, Tardieux, Isabelle, Hakimi, Mohamed-Ali, Bougdour, Alexandre
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6214654/
https://ncbi.nlm.nih.gov/pubmed/30320549
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39887
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