A Toxoplasma dense granule protein, GRA24, modulates the early immune response to infection by promoting a direct and sustained host p38 MAPK activation

Toxoplasma gondii, the causative agent of toxoplasmosis, is an obligate intracellular protozoan parasite that resides inside a parasitophorous vacuole. During infection, Toxoplasma actively remodels the transcriptome of its hosting cells with profound and coupled impact on the host immune response....

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Main Authors: Braun, Laurence, Brenier-Pinchart, Marie-Pierre, Yogavel, Manickam, Curt-Varesano, Aurélie, Curt-Bertini, Rose-Laurence, Hussain, Tahir, Kieffer-Jaquinod, Sylvie, Coute, Yohann, Pelloux, Hervé, Tardieux, Isabelle, Sharma, Amit, Belrhali, Hassan, Bougdour, Alexandre, Hakimi, Mohamed-Ali
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3782045/
https://ncbi.nlm.nih.gov/pubmed/24043761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20130103
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