Cell-autonomous Toxoplasma killing program requires Irgm2 but not its microbe vacuolar localization

Interferon-inducible GTPases, such as immunity-related GTPases (IRGs) and guanylate-binding proteins (GBPs), are essential for cell-autonomous immunity against a wide variety of intracellular pathogens including Toxoplasma. IRGs comprise regulatory and effector subfamily proteins. Regulatory IRGs Ir...

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Detalhes bibliográficos
Publicado no:Life Sci Alliance
Main Authors: Pradipta, Ariel, Sasai, Miwa, Motani, Kou, Ma, Ji Su, Lee, Youngae, Kosako, Hidetaka, Yamamoto, Masahiro
Formato: Artigo
Idioma:Inglês
Publicado em: Life Science Alliance LLC 2021
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8200298/
https://ncbi.nlm.nih.gov/pubmed/34078740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.26508/lsa.202000960
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