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Ketyl radical reactivity via atom transfer catalysis

Single-electron reduction of a carbonyl to a ketyl enables access to a polarity-reversed platform of reactivity for this cornerstone functional group. However, the synthetic utility of the ketyl radical is hindered by the strong reductants necessary for its generation, which also limit its reactivit...

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Détails bibliographiques
Publié dans:Science
Auteurs principaux: Wang, Lu, Lear, Jeremy M., Rafferty, Sean M., Fosu, Stacy C., Nagib, David A.
Format: Artigo
Langue:Inglês
Publié: 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504239/
https://ncbi.nlm.nih.gov/pubmed/30309953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aau1777
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