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Ketyl radical reactivity via atom transfer catalysis

Single-electron reduction of a carbonyl to a ketyl enables access to a polarity-reversed platform of reactivity for this cornerstone functional group. However, the synthetic utility of the ketyl radical is hindered by the strong reductants necessary for its generation, which also limit its reactivit...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Wang, Lu, Lear, Jeremy M., Rafferty, Sean M., Fosu, Stacy C., Nagib, David A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504239/
https://ncbi.nlm.nih.gov/pubmed/30309953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aau1777
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