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Ketyl radical reactivity via atom transfer catalysis

Single-electron reduction of a carbonyl to a ketyl enables access to a polarity-reversed platform of reactivity for this cornerstone functional group. However, the synthetic utility of the ketyl radical is hindered by the strong reductants necessary for its generation, which also limit its reactivit...

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Bibliographic Details
Published in:Science
Main Authors: Wang, Lu, Lear, Jeremy M., Rafferty, Sean M., Fosu, Stacy C., Nagib, David A.
Format: Artigo
Language:Inglês
Published: 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504239/
https://ncbi.nlm.nih.gov/pubmed/30309953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aau1777
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