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CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes
Oligodendrocytes (OLs) support neurons and signal transmission in the central nervous system (CNS) by enwrapping axons with myelin, a lipid-rich membrane structure. We addressed the significance of fatty acid (FA) synthesis in OLs by depleting FA synthase (FASN) from OL progenitor cells (OPCs) in tr...
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| Vydáno v: | eLife |
|---|---|
| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
eLife Sciences Publications, Ltd
2019
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6504237/ https://ncbi.nlm.nih.gov/pubmed/31063129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44702 |
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