CNS myelination and remyelination depend on fatty acid synthesis by oligodendrocytes

Oligodendrocytes (OLs) support neurons and signal transmission in the central nervous system (CNS) by enwrapping axons with myelin, a lipid-rich membrane structure. We addressed the significance of fatty acid (FA) synthesis in OLs by depleting FA synthase (FASN) from OL progenitor cells (OPCs) in tr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Dimas, Penelope, Montani, Laura, Pereira, Jorge A, Moreno, Daniel, Trötzmüller, Martin, Gerber, Joanne, Semenkovich, Clay F, Köfeler, Harald C, Suter, Ueli
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2019
Pynciau:
Neuroscience
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504237/
https://ncbi.nlm.nih.gov/pubmed/31063129
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.44702
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