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De novo fatty acid synthesis by Schwann cells is essential for peripheral nervous system myelination

Myelination calls for a remarkable surge in cell metabolism to facilitate lipid and membrane production. Endogenous fatty acid (FA) synthesis represents a potentially critical process in myelinating glia. Using genetically modified mice, we show that Schwann cell (SC) intrinsic activity of the enzym...

詳細記述

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書誌詳細
出版年:J Cell Biol
主要な著者: Montani, Laura, Pereira, Jorge A., Norrmén, Camilla, Pohl, Hartmut B.F., Tinelli, Elisa, Trötzmüller, Martin, Figlia, Gianluca, Dimas, Penelope, von Niederhäusern, Belinda, Schwager, Rachel, Jessberger, Sebastian, Semenkovich, Clay F., Köfeler, Harald C., Suter, Ueli
フォーマット: Artigo
言語:Inglês
出版事項: Rockefeller University Press 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5881495/
https://ncbi.nlm.nih.gov/pubmed/29434029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201706010
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