Bloom syndrome protein restrains innate immune sensing of micronuclei by cGAS

Cellular innate immune sensors of DNA are essential for host defense against invading pathogens. However, the presence of self-DNA inside cells poses a risk of triggering unchecked immune responses. The mechanisms limiting induction of inflammation by self-DNA are poorly understood. BLM RecQ–like he...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Exp Med
Egile Nagusiak: Gratia, Matthieu, Rodero, Mathieu P., Conrad, Cécile, Bou Samra, Elias, Maurin, Mathieu, Rice, Gillian I., Duffy, Darragh, Revy, Patrick, Petit, Florence, Dale, Russell C., Crow, Yanick J., Amor-Gueret, Mounira, Manel, Nicolas
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2019
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6504208/
https://ncbi.nlm.nih.gov/pubmed/30936263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181329
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak