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Possible anti-recombinogenic role of Bloom’s syndrome helicase in double-strand break processing
Bloom’s syndrome (BS) which associates genetic instability and predisposition to cancer is caused by mutations in the BLM gene encoding a RecQ family 3′–5′ DNA helicase. It has been proposed that the generation of genetic instability in BS cells could result from an aberrant non-homologous DNA end j...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2003
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC275476/ https://ncbi.nlm.nih.gov/pubmed/14576316 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkg834 |
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