Possible anti-recombinogenic role of Bloom’s syndrome helicase in double-strand break processing
Bloom’s syndrome (BS) which associates genetic instability and predisposition to cancer is caused by mutations in the BLM gene encoding a RecQ family 3′–5′ DNA helicase. It has been proposed that the generation of genetic instability in BS cells could result from an aberrant non-homologous DNA end j...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC275476/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14576316/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkg834 |
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