Association of Variants in PINX1 and TREM2 With Late-Onset Alzheimer Disease

IMPORTANCE: Genetic causes of late-onset Alzheimer disease (LOAD) are not completely explained by known genetic loci. Whole-exome and whole-genome sequencing can improve the understanding of the causes of LOAD and provide initial steps required to identify potential therapeutic targets. OBJECTIVE: T...

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Publicat a:JAMA Neurol
Autors principals: Tosto, Giuseppe, Vardarajan, Badri, Sariya, Sanjeev, Brickman, Adam M., Andrews, Howard, Manly, Jennifer J., Schupf, Nicole, Reyes-Dumeyer, Dolly, Lantigua, Rafael, Bennett, David A., De Jager, Phillip L., Mayeux, Richard
Format: Artigo
Idioma:Inglês
Publicat: American Medical Association 2019
Matèries:
Original Investigation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6503572/
https://ncbi.nlm.nih.gov/pubmed/31058951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jamaneurol.2019.1066
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