Whole genome sequencing of Caribbean Hispanic families with late‐onset Alzheimer's disease

OBJECTIVE: To identify rare causal variants underlying known loci that segregate with late‐onset Alzheimer's disease (LOAD) in multiplex families. METHODS: We analyzed whole genome sequences (WGS) from 351 members of 67 Caribbean Hispanic (CH) families from Dominican Republic and New York multi...

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Bibliografiske detaljer
Udgivet i:Ann Clin Transl Neurol
Main Authors: Vardarajan, Badri N., Barral, Sandra, Jaworski, James, Beecham, Gary W., Blue, Elizabeth, Tosto, Giuseppe, Reyes‐Dumeyer, Dolly, Medrano, Martin, Lantigua, Rafael, Naj, Adam, Thornton, Timothy, DeStefano, Anita, Martin, Eden, Wang, Li‐San, Brown, Lisa, Bush, William, van Duijn, Cornelia, Goate, Allison, Farrer, Lindsay, Haines, Jonathan L., Boerwinkle, Eric, Schellenberg, Gerard, Wijsman, Ellen, Pericak‐Vance, Margaret A., Mayeux, Richard
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2018
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Research Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899906/
https://ncbi.nlm.nih.gov/pubmed/29688227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.537
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