Whole genome sequencing of Caribbean Hispanic families with late‐onset Alzheimer's disease

OBJECTIVE: To identify rare causal variants underlying known loci that segregate with late‐onset Alzheimer's disease (LOAD) in multiplex families. METHODS: We analyzed whole genome sequences (WGS) from 351 members of 67 Caribbean Hispanic (CH) families from Dominican Republic and New York multi...

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書目詳細資料
發表在:Ann Clin Transl Neurol
Main Authors: Vardarajan, Badri N., Barral, Sandra, Jaworski, James, Beecham, Gary W., Blue, Elizabeth, Tosto, Giuseppe, Reyes‐Dumeyer, Dolly, Medrano, Martin, Lantigua, Rafael, Naj, Adam, Thornton, Timothy, DeStefano, Anita, Martin, Eden, Wang, Li‐San, Brown, Lisa, Bush, William, van Duijn, Cornelia, Goate, Allison, Farrer, Lindsay, Haines, Jonathan L., Boerwinkle, Eric, Schellenberg, Gerard, Wijsman, Ellen, Pericak‐Vance, Margaret A., Mayeux, Richard
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
主題:
Research Articles
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899906/
https://ncbi.nlm.nih.gov/pubmed/29688227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.537
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