Whole genome sequencing of Caribbean Hispanic families with late‐onset Alzheimer's disease

OBJECTIVE: To identify rare causal variants underlying known loci that segregate with late‐onset Alzheimer's disease (LOAD) in multiplex families. METHODS: We analyzed whole genome sequences (WGS) from 351 members of 67 Caribbean Hispanic (CH) families from Dominican Republic and New York multi...

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Detalhes bibliográficos
Publicado no:Ann Clin Transl Neurol
Main Authors: Vardarajan, Badri N., Barral, Sandra, Jaworski, James, Beecham, Gary W., Blue, Elizabeth, Tosto, Giuseppe, Reyes‐Dumeyer, Dolly, Medrano, Martin, Lantigua, Rafael, Naj, Adam, Thornton, Timothy, DeStefano, Anita, Martin, Eden, Wang, Li‐San, Brown, Lisa, Bush, William, van Duijn, Cornelia, Goate, Allison, Farrer, Lindsay, Haines, Jonathan L., Boerwinkle, Eric, Schellenberg, Gerard, Wijsman, Ellen, Pericak‐Vance, Margaret A., Mayeux, Richard
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5899906/
https://ncbi.nlm.nih.gov/pubmed/29688227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/acn3.537
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