Cardiomyocyte-GSK-3α promotes mPTP opening and heart failure in mice with chronic pressure overload

Chronic pressure-overload (PO)- induced cardiomyopathy is one of the leading causes of left ventricular (LV) remodeling and heart failure. The role of the α isoform of glycogen synthase kinase-3 (GSK-3α) in PO-induced cardiac remodeling is unclear and its downstream molecular targets are largely unk...

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Detalhes bibliográficos
Publicado no:J Mol Cell Cardiol
Main Authors: Ahmad, Firdos, Singh, Anand P., Tomar, Dhanendra, Rahmani, Mohamed, Zhang, Qinkun, Woodgett, James R., Tilley, Douglas G., Lal, Hind, Force, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6502694/
https://ncbi.nlm.nih.gov/pubmed/30928428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2019.03.020
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