Cardiomyocyte-specific deletion of Gsk3α mitigates post-myocardial infarction remodeling, contractile dysfunction, and heart failure

BACKGROUND: Injury due to myocardial infarction (MI) is largely irreversible. Once an infarct has occurred, the clinical goal becomes limiting remodeling, preserving left ventricular (LV) function and preventing heart failure. While traditional approaches (e.g. β-blockers) partially preserve LV func...

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Main Authors: Ahmad, Firdos, Lal, Hind, Zhou, Jibin, Vagnozzi, Ronald J., Yu, Justine E., Shang, Xiying, Woodgett, James R., Gao, Erhe, Force, Thomas
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142642/
https://ncbi.nlm.nih.gov/pubmed/25125302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2014.04.068
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