Cardiomyocyte-specific deletion of Gsk3α mitigates post-myocardial infarction remodeling, contractile dysfunction, and heart failure

BACKGROUND: Injury due to myocardial infarction (MI) is largely irreversible. Once an infarct has occurred, the clinical goal becomes limiting remodeling, preserving left ventricular (LV) function and preventing heart failure. While traditional approaches (e.g. β-blockers) partially preserve LV func...

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Hlavní autoři: Ahmad, Firdos, Lal, Hind, Zhou, Jibin, Vagnozzi, Ronald J., Yu, Justine E., Shang, Xiying, Woodgett, James R., Gao, Erhe, Force, Thomas
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142642/
https://ncbi.nlm.nih.gov/pubmed/25125302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2014.04.068
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