Cardiomyocyte-specific deletion of Gsk3α mitigates post-myocardial infarction remodeling, contractile dysfunction, and heart failure

BACKGROUND: Injury due to myocardial infarction (MI) is largely irreversible. Once an infarct has occurred, the clinical goal becomes limiting remodeling, preserving left ventricular (LV) function and preventing heart failure. While traditional approaches (e.g. β-blockers) partially preserve LV func...

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Bibliographische Detailangaben
Hauptverfasser: Ahmad, Firdos, Lal, Hind, Zhou, Jibin, Vagnozzi, Ronald J., Yu, Justine E., Shang, Xiying, Woodgett, James R., Gao, Erhe, Force, Thomas
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4142642/
https://ncbi.nlm.nih.gov/pubmed/25125302
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2014.04.068
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