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Cardiomyocyte-specific deletion of Gsk3α mitigates post-myocardial infarction remodeling, contractile dysfunction, and heart failure
BACKGROUND: Injury due to myocardial infarction (MI) is largely irreversible. Once an infarct has occurred, the clinical goal becomes limiting remodeling, preserving left ventricular (LV) function and preventing heart failure. While traditional approaches (e.g. β-blockers) partially preserve LV func...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4142642/ https://ncbi.nlm.nih.gov/pubmed/25125302 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jacc.2014.04.068 |
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