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Use of human induced pluripotent stem cell-derived cardiomyocytes to assess drug cardiotoxicity
Cardiotoxicity has historically been a major cause of drug removal from the pharmaceutical market. Several chemotherapeutic compounds have been noted for their propensities to induce dangerous cardiac-specific side effects such as arrhythmias or cardiomyocyte apoptosis. However, improved preclinical...
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| 出版年: | Nat Protoc |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6502639/ https://ncbi.nlm.nih.gov/pubmed/30413796 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41596-018-0076-8 |
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