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The Protease WSS1A, the Endonuclease MUS81, and the Phosphodiesterase TDP1 Are Involved in Independent Pathways of DNA-protein Crosslink Repair in Plants

DNA–protein crosslinks (DPCs) represent a severe threat to the genome integrity; however, the main mechanisms of DPC repair were only recently elucidated in humans and yeast. Here we define the pathways for DPC repair in plants. Using CRISPR/Cas9, we could show that only one of two homologs of the u...

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Библиографические подробности
Опубликовано в: :Plant Cell
Главные авторы: Enderle, Janina, Dorn, Annika, Beying, Natalja, Trapp, Oliver, Puchta, Holger
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Plant Biologists 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501609/
https://ncbi.nlm.nih.gov/pubmed/30760561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1105/tpc.18.00824
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