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Identification of a novel quinoline-based DNA demethylating compound highly potent in cancer cells
BACKGROUND: DNA methyltransferases (DNMTs) are epigenetic enzymes involved in embryonic development, cell differentiation, epithelial to mesenchymal transition, and control of gene expression, whose overexpression or enhanced catalytic activity has been widely reported in cancer initiation and progr...
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| 出版年: | Clin Epigenetics |
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| 主要な著者: | , , , , , , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6501426/ https://ncbi.nlm.nih.gov/pubmed/31060628 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-019-0663-8 |
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