High Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling During Successful Immune Checkpoint Cancer Therapy

While current immune checkpoint therapy (ICT) mainly targets lymphoid cells, it is associated with a broader remodeling of the tumor micro-environment. Here, using complementary forms of high dimensional profiling, we define differences across all hematopoietic cells from syngeneic mouse tumors duri...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Gubin, Matthew M., Esaulova, Ekaterina, Ward, Jeffrey P., Malkova, Olga N., Runci, Daniele, Wong, Pamela, Noguchi, Takuro, Arthur, Cora D., Meng, Wei, Alspach, Elise, Medrano, Ruan F.V., Fronick, Catrina, Fehlings, Michael, Newell, Evan W., Fulton, Robert S., Sheehan, Kathleen C.F., Oh, Stephen T., Schreiber, Robert D., Artyomov, Maxim N.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501221/
https://ncbi.nlm.nih.gov/pubmed/30343900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.030
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