High Dimensional Analysis Delineates Myeloid and Lymphoid Compartment Remodeling During Successful Immune Checkpoint Cancer Therapy

While current immune checkpoint therapy (ICT) mainly targets lymphoid cells, it is associated with a broader remodeling of the tumor micro-environment. Here, using complementary forms of high dimensional profiling, we define differences across all hematopoietic cells from syngeneic mouse tumors duri...

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Pubblicato in:Cell
Autori principali: Gubin, Matthew M., Esaulova, Ekaterina, Ward, Jeffrey P., Malkova, Olga N., Runci, Daniele, Wong, Pamela, Noguchi, Takuro, Arthur, Cora D., Meng, Wei, Alspach, Elise, Medrano, Ruan F.V., Fronick, Catrina, Fehlings, Michael, Newell, Evan W., Fulton, Robert S., Sheehan, Kathleen C.F., Oh, Stephen T., Schreiber, Robert D., Artyomov, Maxim N.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6501221/
https://ncbi.nlm.nih.gov/pubmed/30343900
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.030
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