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Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion

Intrinsically disordered proteins (IDPs) and their conformational transitions play an important role in neurotransmitter release at the neuronal synapse. Here, the SNARE proteins are essential by forming the SNARE complex that drives vesicular membrane fusion. While it is widely accepted that the SN...

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Podrobná bibliografie
Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Lakomek, Nils-Alexander, Yavuz, Halenur, Jahn, Reinhard, Pérez-Lara, Ángel
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500178/
https://ncbi.nlm.nih.gov/pubmed/30975750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813194116
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