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Munc18-Bound Syntaxin Readily Forms SNARE Complexes with Synaptobrevin in Native Plasma Membranes

Munc18–1, a protein essential for regulated exocytosis in neurons and neuroendocrine cells, belongs to the family of Sec1/Munc18-like (SM) proteins. In vitro, Munc18–1 forms a tight complex with the SNARE syntaxin 1, in which syntaxin is stabilized in a closed conformation. Since closed syntaxin is...

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Xehetasun bibliografikoak
Egile Nagusiak: Zilly, Felipe E, Sørensen, Jakob B, Jahn, Reinhard, Lang, Thorsten
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2006
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1570500/
https://ncbi.nlm.nih.gov/pubmed/17002520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pbio.0040330
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