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Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion
Intrinsically disordered proteins (IDPs) and their conformational transitions play an important role in neurotransmitter release at the neuronal synapse. Here, the SNARE proteins are essential by forming the SNARE complex that drives vesicular membrane fusion. While it is widely accepted that the SN...
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| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2019
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6500178/ https://ncbi.nlm.nih.gov/pubmed/30975750 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813194116 |
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