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Structural dynamics and transient lipid binding of synaptobrevin-2 tune SNARE assembly and membrane fusion

Intrinsically disordered proteins (IDPs) and their conformational transitions play an important role in neurotransmitter release at the neuronal synapse. Here, the SNARE proteins are essential by forming the SNARE complex that drives vesicular membrane fusion. While it is widely accepted that the SN...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Lakomek, Nils-Alexander, Yavuz, Halenur, Jahn, Reinhard, Pérez-Lara, Ángel
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6500178/
https://ncbi.nlm.nih.gov/pubmed/30975750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813194116
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