α-SNAP Interferes with the Zippering of the SNARE Protein Membrane Fusion Machinery

Neuronal exocytosis is mediated by soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins. Before fusion, SNARE proteins form complexes bridging the membrane followed by assembly toward the C-terminal membrane anchors, thus initiating membrane fusion. After fusion, th...

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Главные авторы: Park, Yongsoo, Vennekate, Wensi, Yavuz, Halenur, Preobraschenski, Julia, Hernandez, Javier M., Riedel, Dietmar, Walla, Peter Jomo, Jahn, Reinhard
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2014
Предметы:
Neurobiology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047401/
https://ncbi.nlm.nih.gov/pubmed/24778182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.556803
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