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Commonly used FRET fluorophores promote collapse of an otherwise disordered protein
The dimensions that unfolded proteins, including intrinsically disordered proteins (IDPs), adopt in the absence of denaturant remain controversial. We developed an analysis procedure for small-angle X-ray scattering (SAXS) profiles and used it to demonstrate that even relatively hydrophobic IDPs rem...
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| 出版年: | Proc Natl Acad Sci U S A |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2019
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6500129/ https://ncbi.nlm.nih.gov/pubmed/30992378 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1813038116 |
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