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Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water

A substantial fraction of the proteome is intrinsically disordered, and even well-folded proteins adopt non-native geometries during synthesis, folding, transport, and turnover. Characterization of intrinsically disordered proteins (IDPs) is challenging, in part because of a lack of accurate physica...

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Detalhes bibliográficos
Publicado no:Science
Main Authors: Riback, Joshua A., Bowman, Micayla A., Zmyslowski, Adam M., Knoverek, Catherine R., Jumper, John M., Hinshaw, James R., Kaye, Emily B., Freed, Karl F., Clark, Patricia L., Sosnick, Tobin R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5959285/
https://ncbi.nlm.nih.gov/pubmed/29026044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aan5774
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