SWI/SNF component ARID1A restrains pancreatic neoplasia formation

OBJECTIVE: ARID1A is commonly mutated in pancreatic ductal adenocarcinoma (PDAC), but the functional effects of ARID1A mutations in the pancreas are unclear. Understanding the molecular mechanisms that drive PDAC formation may lead to novel therapies. DESIGN: Concurrent conditional Arid1a deletion a...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Wang, Sam C, Nassour, Ibrahim, Xiao, Shu, Zhang, Shuyuan, Luo, Xin, Lee, Jeon, Li, Lin, Sun, Xuxu, Nguyen, Liem H, Chuang, Jen-Chieh, Peng, Lan, Daigle, Scott, Shen, Jeanne, Zhu, Hao
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2019
Assuntos:
Pancreas
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499717/
https://ncbi.nlm.nih.gov/pubmed/30315093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2017-315490
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