SWI/SNF component ARID1A restrains pancreatic neoplasia formation

OBJECTIVE: ARID1A is commonly mutated in pancreatic ductal adenocarcinoma (PDAC), but the functional effects of ARID1A mutations in the pancreas are unclear. Understanding the molecular mechanisms that drive PDAC formation may lead to novel therapies. DESIGN: Concurrent conditional Arid1a deletion a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Gut
Egile Nagusiak: Wang, Sam C, Nassour, Ibrahim, Xiao, Shu, Zhang, Shuyuan, Luo, Xin, Lee, Jeon, Li, Lin, Sun, Xuxu, Nguyen, Liem H, Chuang, Jen-Chieh, Peng, Lan, Daigle, Scott, Shen, Jeanne, Zhu, Hao
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BMJ Publishing Group 2019
Gaiak:
Pancreas
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499717/
https://ncbi.nlm.nih.gov/pubmed/30315093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2017-315490
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