GIPC proteins negatively modulate Plexind1 signaling during vascular development

Semaphorins (SEMAs) and their Plexin (PLXN) receptors are central regulators of metazoan cellular communication. SEMA-PLXND1 signaling plays important roles in cardiovascular, nervous, and immune system development, and cancer biology. However, little is known about the molecular mechanisms that mod...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Carretero-Ortega, Jorge, Chhangawala, Zinal, Hunt, Shane, Narvaez, Carlos, Menéndez-González, Javier, Gay, Carl M, Zygmunt, Tomasz, Li, Xiaochun, Torres-Vázquez, Jesús
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2019
Matèries:
Developmental Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499541/
https://ncbi.nlm.nih.gov/pubmed/31050647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.30454
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