Semaphorin-PlexinD1 Signaling Limits Angiogenic Potential via the VEGF Decoy Receptor sFlt1

Sprouting angiogenesis expands the embryonic vasculature enabling survival and homeostasis. Yet how the angiogenic capacity to form sprouts is allocated among endothelial cells (ECs) to guarantee the reproducible anatomy of stereotypical vascular beds remains unclear. Here we show that Sema-PlxnD1 s...

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Main Authors: Zygmunt, Tomasz, Gay, Carl Michael, Blondelle, Jordan, Singh, Manvendra K., Flaherty, Kathleen McCrone, Means, Paula Casey, Herwig, Lukas, Krudewig, Alice, Belting, Heinz-Georg, Affolter, Markus, Epstein, Jonathan A., Torres-Vázquez, Jesús
格式: Artigo
語言:Inglês
出版: 2011
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3156278/
https://ncbi.nlm.nih.gov/pubmed/21802375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.06.033
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