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Semaphorin 3E/PlexinD1 signaling is required for cardiac ventricular compaction

Left ventricular noncompaction (LVNC) is one of the most common forms of genetic cardiomyopathy characterized by excessive trabeculation and impaired myocardial compaction during fetal development. Patients with LVNC are at higher risk of developing left/right ventricular failure or both. Although t...

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Publicado en:JCI Insight
Main Authors: Sandireddy, Reddemma, Cibi, Dasan Mary, Gupta, Priyanka, Singh, Anamika, Tee, Nicole, Uemura, Akiyoshi, Epstein, Jonathan A., Singh, Manvendra K.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Clinical Investigation 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6777811/
https://ncbi.nlm.nih.gov/pubmed/31434798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.125908
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