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Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects
PlexinD1 is a membrane-bound receptor that mediates signals derived from class 3 secreted semaphorins. Although semaphorin signaling in axon guidance in the nervous system has been extensively studied, functions outside the nervous system including important roles in vascular patterning have also be...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2650856/ https://ncbi.nlm.nih.gov/pubmed/18992737 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.09.031 |
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