Tie2Cre-mediated inactivation of plexinD1 results in congenital heart, vascular and skeletal defects

PlexinD1 is a membrane-bound receptor that mediates signals derived from class 3 secreted semaphorins. Although semaphorin signaling in axon guidance in the nervous system has been extensively studied, functions outside the nervous system including important roles in vascular patterning have also be...

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Main Authors: Zhang, Ying, Singh, Manvendra K., Degenhardt, Karl R., Lu, Min Min, Bennett, Jean, Yoshida, Yutaka, Epstein, Jonathan A.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650856/
https://ncbi.nlm.nih.gov/pubmed/18992737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.09.031
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