DNA (de)methylation in embryonic stem cells controls CTCF-dependent chromatin boundaries

Coordinated changes of DNA (de)methylation, nucleosome positioning, and chromatin binding of the architectural protein CTCF play an important role for establishing cell-type–specific chromatin states during differentiation. To elucidate molecular mechanisms that link these processes, we studied the...

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Publicat a:Genome Res
Autors principals: Wiehle, Laura, Thorn, Graeme J., Raddatz, Günter, Clarkson, Christopher T., Rippe, Karsten, Lyko, Frank, Breiling, Achim, Teif, Vladimir B.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2019
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499307/
https://ncbi.nlm.nih.gov/pubmed/30948436
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.239707.118
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