Sequential Immunization With Live-Attenuated Chimeric Hemagglutinin-Based Vaccines Confers Heterosubtypic Immunity Against Influenza A Viruses in a Preclinical Ferret Model

Due to continuous antigenic drift and occasional antigenic shift, influenza viruses escape from human adaptive immunity resulting in significant morbidity and mortality in humans. Therefore, to avoid the need for annual reformulation and readministration of seasonal influenza virus vaccines, we are...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Front Immunol
Главные авторы: Liu, Wen-Chun, Nachbagauer, Raffael, Stadlbauer, Daniel, Solórzano, Alicia, Berlanda-Scorza, Francesco, García-Sastre, Adolfo, Palese, Peter, Krammer, Florian, Albrecht, Randy A.
Формат: Artigo
Язык:Inglês
Опубликовано: Frontiers Media S.A. 2019
Предметы:
Immunology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6499175/
https://ncbi.nlm.nih.gov/pubmed/31105689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00756
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы