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p95HER2–T cell bispecific antibody for breast cancer treatment
T cell bispecific antibodies (TCBs) are engineered molecules that include, within a single entity, binding sites to the T cell receptor and to tumor-associated or tumor-specific antigens. The receptor tyrosine kinase HER2 is a tumor-associated antigen in ~25% of breast cancers. TCBs targeting HER2 m...
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Publicado no: | Sci Transl Med |
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Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6498439/ https://ncbi.nlm.nih.gov/pubmed/30282693 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aat1445 |
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