Development of an ORF45-Derived Peptide To Inhibit the Sustained RSK Activation and Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus

Eitemau Tebyg

• Activation of p90 Ribosomal S6 Kinase by ORF45 of Kaposi's Sarcoma-Associated Herpesvirus and Its Role in Viral Lytic Replication
  gan: Kuang, Ersheng, et al.
  Cyhoeddwyd: (2008)
• ORF45-Mediated Prolonged c-Fos Accumulation Accelerates Viral Transcription during the Late Stage of Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus
  gan: Li, Xiaojuan, et al.
  Cyhoeddwyd: (2015)
• Mechanism of Sustained Activation of Ribosomal S6 Kinase (RSK) and ERK by Kaposi Sarcoma-associated Herpesvirus ORF45: MULTIPROTEIN COMPLEXES RETAIN ACTIVE PHOSPHORYLATED ERK AND RSK AND PROTECT THEM FROM DEPHOSPHORYLATION
  gan: Kuang, Ersheng, et al.
  Cyhoeddwyd: (2009)
• Activation of RSK and ERK MAPK kinases by ORF45 of Kaposi's sarcoma-associated herpesvirus
  gan: Zhu, F, et al.
  Cyhoeddwyd: (2009)
• Phosphorylation of Eukaryotic Translation Initiation Factor 4B (EIF4B) by Open Reading Frame 45/p90 Ribosomal S6 Kinase (ORF45/RSK) Signaling Axis Facilitates Protein Translation during Kaposi Sarcoma-associated Herpesvirus (KSHV) Lytic Replication
  gan: Kuang, Ersheng, et al.
  Cyhoeddwyd: (2011)