Development of an ORF45-Derived Peptide To Inhibit the Sustained RSK Activation and Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus

The lytic replication of Kaposi’s sarcoma-associated herpesvirus (KSHV) requires sustained extracellular signal-regulated kinase (ERK)-p90 ribosomal S6 kinase (RSK) activation, which is induced by an immediate early (IE) gene-encoded tegument protein called ORF45, to promote the late transcription a...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Li, Xiaojuan, Huang, Lu, Xiao, Yunjun, Yao, Xiangyang, Long, Xubing, Zhu, Fanxiu, Kuang, Ersheng
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2019
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498066/
https://ncbi.nlm.nih.gov/pubmed/30842327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02154-18
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk