ORF45-Mediated Prolonged c-Fos Accumulation Accelerates Viral Transcription during the Late Stage of Lytic Replication of Kaposi's Sarcoma-Associated Herpesvirus

Kaposi's sarcoma-associated herpesvirus (KSHV) encodes multiple viral proteins that activate extracellular signal-regulated kinase (ERK)–mitogen-activated protein kinase (MAPK) cascades. One of these viral proteins, ORF45, mediates sustained ERK-p90 ribosomal S6 kinase (RSK) activation during K...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Li, Xiaojuan, Du, Shumin, Avey, Denis, Li, Yuqing, Zhu, Fanxiu, Kuang, Ersheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468511/
https://ncbi.nlm.nih.gov/pubmed/25903346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00274-15
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