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Unique Interferon Pathway Regulation by the Andes Virus Nucleocapsid Protein Is Conferred by Phosphorylation of Serine 386

Andes virus (ANDV) causes hantavirus pulmonary syndrome (HPS) and is the only hantavirus shown to spread person to person and cause a highly lethal HPS-like disease in Syrian hamsters. The unique ability of ANDV N protein to inhibit beta interferon (IFNβ) induction may contribute to its virulence an...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Simons, Matthew J., Gorbunova, Elena E., Mackow, Erich R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6498058/
https://ncbi.nlm.nih.gov/pubmed/30867297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00338-19
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