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The Andes Virus Nucleocapsid Protein Directs Basal Endothelial Cell Permeability by Activating RhoA

Andes virus (ANDV) predominantly infects microvascular endothelial cells (MECs) and nonlytically causes an acute pulmonary edema termed hantavirus pulmonary syndrome (HPS). In HPS patients, virtually every pulmonary MEC is infected, MECs are enlarged, and infection results in vascular leakage and hi...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Gorbunova, Elena E., Simons, Matthew J., Gavrilovskaya, Irina N., Mackow, Erich R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5080385/
https://ncbi.nlm.nih.gov/pubmed/27795403
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01747-16
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