Hantaviruses Direct Endothelial Cell Permeability by Sensitizing Cells to the Vascular Permeability Factor VEGF, while Angiopoietin 1 and Sphingosine 1-Phosphate Inhibit Hantavirus-Directed Permeability

Hantaviruses infect human endothelial cells and cause two vascular permeability-based diseases: hemorrhagic fever with renal syndrome and hantavirus pulmonary syndrome. Hantavirus infection alone does not permeabilize endothelial cell monolayers. However, pathogenic hantaviruses inhibit the function...

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Hlavní autoři: Gavrilovskaya, Irina N., Gorbunova, Elena E., Mackow, Natalie A., Mackow, Erich R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395149/
https://ncbi.nlm.nih.gov/pubmed/18367532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02397-07
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