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VEGFR2 and Src Kinase Inhibitors Suppress Andes Virus-Induced Endothelial Cell Permeability

Hantaviruses predominantly infect human endothelial cells and, in the absence of cell lysis, cause two diseases resulting from increased vascular permeability. Andes virus (ANDV) causes a highly lethal acute pulmonary edema termed hantavirus pulmonary syndrome (HPS). ANDV infection enhances the perm...

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Bibliographic Details
Main Authors: Gorbunova, Elena E., Gavrilovskaya, Irina N., Pepini, Timothy, Mackow, Erich R.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3067787/
https://ncbi.nlm.nih.gov/pubmed/21177802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02319-10
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